See [[https://tex.stackexchange.com/questions/365939/cannot-open-dde-link-to-problems-with-adobe-acrobat-pro-dc-2017-and-winedt]] If you can't upgrade to the latest version of WinEdt, you can instead open a local copy of the file Adobe.edt from the Options menu -> Options Interface dialog -> Advanced Configuration -> PDF Macros -> Adobe Blues. In this file, replace the line at the very end of it {{{// Assign(!"Acro-DDE_Service",!"AcroviewR11");}}} with the following {{{Assign(!"Acro-DDE_Service",!"AcroviewA17");}}} then save the file and restart WinEdt. Addendum: Name of the DDE service for different versions of Adobe DC {{{ Adobe Reader DC 2015: AcroviewR15 Acrobat DC Pro 2015: AcroviewA15 Adobe Reader DC 2017: AcroviewR17 Acrobat DC Pro 2017: AcroviewA17 Adobe Reader DC 2018: AcroviewR18 Acrobat DC Pro 2018: AcroviewA18 }}} Unless Adobe changes its naming convention, for future versions it suffices to change the last two digits according to the year version.